For software engineering, if two code fragments are closely similar with minor modifications or even identical due to a copy-paste behavior, that is called software/code clone.Code clones can cause trouble in software maintenance and debugging process because identifying all Composters copied compromised code fragments in other locations is time-co
Cytochromes P450 located in the endoplasmic reticulum require NADPH cytochrome P450 oxidoreductase (POR) for their catalytic activities.Mutations in POR cause multiple disorders in humans related to the biosynthesis of steroid hormones and also affect drug-metabolizing cytochrome P450 activities.Electron transfer in POR occurs from NADH to FAD to F
Public policies on care services designed by the US government are not exempt from certain ideological dimension, which contextualizes the system of providing those services.Taking as starting point a critical review of the concepts Dishwasher Filter of spatial justice and social segregation, a geostatistical methodology multilevel is designed to s
Anne Rodallec,1 Guillaume Sicard,1 Sarah Giacometti,1 Manon Carré,1 Bertrand Pourroy,2 Fanny Bouquet,3 Ariel Savina,3 Bruno Lacarelle,1 Joseph Ciccolini,1 Raphaelle Fanciullino1 1SMARTc Unit, Laboratory of Pharmacokinetics and Toxicology UFR Pharmacy, Center for Research on Cancer of Marseille, Inserm UMR1068, CNRS UMR7258, Aix Marseille Uni
Flags Recombinant adeno-associated virus (rAAV) platforms hold promise for in vivo gene therapy but are undermined by the undesirable transduction of antigen presenting cells (APCs), which in turn can trigger host immunity towards rAAV-expressed transgene products.In light of recent adverse events in patients receiving high systemic AAV vector dose